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Home Page > Pharmaceutical
Litigation > Permax
What is Permax?
Permax or pergolide mesylate is a potent dopamine receptor
agonist. It is indicated as adjunctive treatment to levodopa/carbidopa
in the management of the signs and symptoms of Parkinson’s
disease. It works by stimulating the central nervous system
to help treat the symptoms of Parkinson’s disease.
Our firm is currently investigating potential claims against
the maker of Permax for potentially fatal side effects
involving heart valve damage. If you or a loved one has
been affected by Permax, please contact us today.
Permax FDA Warnings and Side Effects
The first warning issued to consumers regarding Permax was
in 2003. The Food and Drug Administration requested Eli
Lilly to inform users of the drug that it could cause drowsiness
during normal day to day activities including driving motor
vehicles.
Recently, two more studies released by The New England
Journal of Medicine in January 2007 indicated the
use of the dopamine agonists pergolide (Permax) and cabergoline
is associated with an increased risk of cardiac valve regurgitation.
This increase in cardiac valve damage was even more prominent
when it was administered in high doses over a long period
of time. These studies were based upon people between 40
and 80 years of age that received at least two prescriptions
for anti-Parkinson’s medications between January
1988 and August 2005.
Permax warnings and precautions
Recent studies have shown rare cases of pleutitis, pleural
effusion, pleural fibrosis, pericarditis, pericardial effusion,
cardiac valvuopathy involving one or more valves or retroperitoneal
fibrosis in people taking Permax or pergolide. There have
been reports of patients falling asleep during activities
of daily living including operating motor vehicles which
can lead to accidents.
Possible side effects of Permax include:
- leaky heart valves
- valvular heart disease
- heart-valve damage
- cardiac valvulopathy
- pulmonary fibrosis (retroperitoneal, pleural, and pericardial
fibrosis)
Permax Lawyers
Our attorneys have years of experience handling drug litigation
and understand the issues of people injured by dangerous
drugs. If you are curious or are just not sure how to handle
your situation and it involves Permax, pick up the phone
and call us. Our lawyers can help you make an educated
decision on how to handle your Permax situation and decide
whether you need to file a lawsuit. If you do need to file
a lawsuit, we will help you find the answers you are looking
for, diligently represent you and stand up to any negligent
party involved in your hardship.
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